PRP is a coherent, ecological and synergistic treatment concept.
It revives the age-old principle of vis medicatrix naturae – or the body’s ability to heal itself.
The idea behind PRP involves harnessing the body’s healing capacity to treat a specific area.
Only pure and highly concentrated PRP can release the quantity of growth factors required to stimulate cellular regeneration.
PRP’s therapeutic potential is due to the growth factors found in the platelet alpha granules[1] such as the transforming growth factor beta (TGF-β)[2], the vascular endothelial growth factor (VEGF)[3], and the platelet-derived growth factor (PDGF)[4], whose pivotal role in tissue repair has been clearly demonstrated.
1. T. E. Foster, B. L. Puskas, B. R. Mandelbaum, M. B. Gerhardt, and S. A. Rodeo, “Platelet-rich plasma: from basic science to clinical applications,” American Journal of Sports Medicine, vol. 37, no. 11, pp. 2259–2272, 2009.
2. M. Pakyari, A. Farrokhi, M. K. Maharlooei, and A. Ghahary, “Critical role of transforming growth factor beta in different phases of wound healing,” Advances in Wound Care, vol. 2, no. 5, pp. 215–224, 2013.
3. D. I. R. Holmes and I. Zachary, “The vascular endothelial growth factor (VEGF) family: angiogenic factors in health and disease,” Genome Biology, vol. 6, no. 2, article 209, 2005.
4. Donovan, D. Abraham, and J. Norman, “Platelet-derived growth factor signaling in mesenchymal cells,” Frontiers in Bioscience, vol. 18, no. 1, pp. 106–119, 2013.