“Because people are the ends and not the means.”
Kant

PRP is a coherent, ecological and synergistic treatment concept.

It revives the age-old principle of vis medicatrix naturae – or the body’s ability to heal itself.

The idea behind PRP involves harnessing the body’s healing capacity to treat a specific area.

Only pure and highly concentrated PRP can release the quantity of growth factors required to stimulate cellular regeneration.

PRP’s therapeutic potential is due to the growth factors found in the platelet alpha granules[1] such as the transforming growth factor beta (TGF-β)[2], the vascular endothelial growth factor (VEGF)[3], and the platelet-derived growth factor (PDGF)[4], whose pivotal role in tissue repair has been clearly demonstrated.

1. T. E. Foster, B. L. Puskas, B. R. Mandelbaum, M. B. Gerhardt, and S. A. Rodeo, “Platelet-rich plasma: from basic science to clinical applications,” American Journal of Sports Medicine, vol. 37, no. 11, pp. 2259–2272, 2009.
2. M. Pakyari, A. Farrokhi, M. K. Maharlooei, and A. Ghahary, “Critical role of transforming growth factor beta in different phases of wound healing,” Advances in Wound Care, vol. 2, no. 5, pp. 215–224, 2013.
3. D. I. R. Holmes and I. Zachary, “The vascular endothelial growth factor (VEGF) family: angiogenic factors in health and disease,” Genome Biology, vol. 6, no. 2, article 209, 2005.
4. Donovan, D. Abraham, and J. Norman, “Platelet-derived growth factor signaling in mesenchymal cells,” Frontiers in Bioscience, vol. 18, no. 1, pp. 106–119, 2013.

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PRP is a coherent, ecological and synergistic treatment concept.

It revives the age-old principle of vis medicatrix naturae – or the body’s ability to heal itself.

The idea behind PRP involves harnessing the body’s healing capacity to treat a specific area.

Only pure and highly concentrated PRP can release the quantity of growth factors required to stimulate cellular regeneration.

PRP’s therapeutic potential is due to the growth factors found in the platelet alpha granules[1] such as the transforming growth factor beta (TGF-β)[2], the vascular endothelial growth factor (VEGF)[3], and the platelet-derived growth factor (PDGF)[4], whose pivotal role in tissue repair has been clearly demonstrated.

1. T. E. Foster, B. L. Puskas, B. R. Mandelbaum, M. B. Gerhardt, and S. A. Rodeo, “Platelet-rich plasma: from basic science to clinical applications,” American Journal of Sports Medicine, vol. 37, no. 11, pp. 2259–2272, 2009.
2. M. Pakyari, A. Farrokhi, M. K. Maharlooei, and A. Ghahary, “Critical role of transforming growth factor beta in different phases of wound healing,” Advances in Wound Care, vol. 2, no. 5, pp. 215–224, 2013.
3. D. I. R. Holmes and I. Zachary, “The vascular endothelial growth factor (VEGF) family: angiogenic factors in health and disease,” Genome Biology, vol. 6, no. 2, article 209, 2005.
4. Donovan, D. Abraham, and J. Norman, “Platelet-derived growth factor signaling in mesenchymal cells,” Frontiers in Bioscience, vol. 18, no. 1, pp. 106–119, 2013.

Growth FactorSourceFunction
Transforming Growth Factor-beta, TGF-ßPlatelets, extracellular matrix of bone, cartilage matrix, activated TH1 cells and natural killer cells, macrophages/ monocytes and neutrophilsStimulates undifferentiated mesenchymal cell proliferation; regulates endothelial, fibroblastic and osteoblastic mitogenesis; regulates collagen synthesis and collagenase secretion; regulates mitogenic effects of other growth factors; stimulates endothelial chemotaxis and angiogenesis; inhibits macrophage and lymphocyte proliferation
Basic Fibroblast Growth Factor, b FGFPlatelets, macrophages, mesenchymal cells, chondrocytes, osteoblastsPromotes growth and differentiation of chondrocytes and osteoblasts; mitogenetic for mesenchymal cells, chondrocytes and osteoblasts
Platelet Derived Growth Factor, PDG Fa-bPlatelets, osteoblasts, endothelial cells, macrophages, monocytes, smooth muscle cellsMitogenetic for mesenchymal cells and osteoblasts; stimulates chemotaxis and mitogenesis in fibroblast/glial/smooth muscle cells; regulates collagenase secretion and collagen synthesis; stimulates macrophage and neutrophil chemotaxis
Epidermal Growth Factor, EGFPlatelets, macrophages, monocytesStimulates endothelial chemotaxis/angiogenesis; regulates collagenase secretion; stimulates epithelial/mesenchymal mitogenesis
Vascular endothelial growth factor, VEGFPlatelets, endothelial cellsIncreases angiogenesis and vessel permeability, stimulates mitogenesis for endothelial cells
Connective tissue growth factor, CTGFPlatelets through endocytosis from extracellular environment in bone marrow.Promotes angiogenesis, cartilage regeneration, fibrosis and platelet adhesion

A Coherent Production and Treatment Process

To make the most of this natural process, it is critical to understand just how fragile platelets really are and how quickly they degrade the moment they are taken from the body. Spinning must be done gently with a device capable of gradual acceleration. This is why we recommend a centrifuge which we have selected from many other models in order to meet our quality standards.

Time is a very important factor. This is why the process should take only 3 minutes of centrifugation from the moment the blood is drawn to the injection of the PRP.

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A Coherent Production and Treatment Process

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To make the most of this natural process, it is critical to understand just how fragile platelets really are and how quickly they degrade the moment they are taken from the body. Spinning must be done gently with a device capable of gradual acceleration. This is why we recommend a centrifuge which we have selected from many other models in order to meet our quality standards.

Time is a very important factor. This is why the process should take only 3 minutes of centrifugation from the moment the blood is drawn to the injection of the PRP.

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PRP in 3 Minutes

With the WorldPRP kit, you can expect the right amount of platelets (and zero leukocytes or hematocytes), gentle processing and speedy execution for ultra-pure PRP every time.

Safety is another critical point taken into account by health professionals. The WorldPRP kit provides perfectly sterile conditions without the use of needles at any point, eliminating a potential source of accidents.

PRP in 3 Minutes

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With the WorldPRP kit, you can expect the right amount of platelets (and zero leukocytes or hematocytes), gentle processing and speedy execution for ultra-pure PRP every time.

Safety is another critical point taken into account by health professionals. The WorldPRP kit provides perfectly sterile conditions without the use of needles at any point, eliminating a potential source of accidents.